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Drug Safety & Toxicity

Study Code Study Name Species
DS-0 Single dose toxicity
DS-1 Limit Test Rat, Mouse
DS-2 Acute Toxicity Rat, Mouse
DS-3 Maximal Tolerated Dose Dog
DS-4 Irritation and Sensitization tests
DS-5 Acute dermal irritation Rabbit
DS-6 Acute Eye Irritation Rabbit
DS-7 Phototoxicity/Sensitization Mouse
DS-8 Sensitization Guinea pig
DS-9 Repeated Dose Toxicity
DS-10 Subacute Toxicity – Oral Gavage Rat, Dog
DS-11 Subchronic Toxicity – Oral Gavage Rat, Dog
DS-12 Chronic toxicity – Oral Gavage Rat, Dog
DS-13 Carcinogenicity – Oral Gavage Mouse, Rat
DS-14 Genotoxicity
DS-15 Chromosome Aberration test Hamster, Mouse
DS-16 Ames Tests Salmonella Typhimurium, E. coli
DS-17 Micronucleus Mouse
DS-18 Reproductive Toxicity –Oral Gavage
DS-19 Rat Reproductive Toxicity. Fertility (ICH1) Single Generation Reproductive test Rat
DS-20 Female Reproductive Toxicity. Pre and post-natal (ICH2)(F0, F1, F2 generations) Rat
DS-21 Embryotoxicity/Embryo Fetal Development (ICH3) Rat, Rabbit